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CBRG - Computational Biochemistry Research Group
 
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Bioinformatics: In-Depth (Spring 2012)

Please also consult the other webpage of the course!

 

Week/Date Topic Slides Exercise Lecturer
  PART I: Probabilities and Statistics
 
 
22.02 Basic Probabilities and Statistics bi12lec1.pdf
bi10ex1.pdf
SM
29.02
Statistical Estimation and Testing

  SM
07.03
Markov Chains
    SM
14.03
Evolutionary Models and Substitution Matrices
    SM
21.03
Sequence Comparison and Statistical Theory Behind BLAST
    SM
  PART II: Systems Biology      
28.03
 Biochemical reaction network modeling I      IO
04.04
 Biochemical reaction network modeling II lec0404.pdf
ExampleEpo.pdf
Ex1matlab.zip
Ex2.pdf
 IO
18.04
 Bayesian networks I Lec1804.pdf
Ex3.pdf
 IO
25.04
 Bayesian networks II lec2504.pdf
   IO
  PART III: Sequence Analysis and Phylogenetics      
02.05
Multiple Sequence Alignments BioInf2_MSA.pdf
Exercise

Solution

MG
09.05
Orthology, Paralogy, Xenology BioInf2_Orthology.pdf
Exercise
MG
16.05
Basic Phylogenetic Tree Reconstruction PhylogenyInferenceMaria2011_part1.pdf
Exercise
Quizz
MA
23.05
Advanced topics in Phylogenetics PhylogenyInferenceMaria2011_part2.pdf
Exercise
MA
30.05
Positive Selection with Codon Models Positive selection lecture
Exercise MA

Resources

Recommended Readings
New Book describing the state-of the art in statistical methodology for Evolutionary Genomics (Springer):

vol. 1: ISBN 978-1-61779-581-7

vol. 2: ISBN 978-1-61779-584-8

Buy with a 25-35% discount from MA

Darwin
 

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